We are in relentless pursuit of breakthroughs that improve patients' lives. We innovate every day to make the world a better place. It was Charles Pfizer's initial vision, and it still holds true today. Evidence confirms what we instinctively know: that purpose-driven companies perform better, are more inventive, recruit and maintain the best professionals, and know how to unleash the power of those team members. Pfizer's purpose—Breakthroughs that transform patients' lives—powers everything we do and demonstrates our passion for building on our legacy as one of the most meaningful contributors of good to the world. Each word in our purpose has meaning and reflects the value we aim to bring to patients and society. Our purpose guarantees that patients stay at the centre of all we do. We fulfill our purpose by finding the best science in the world, working with others in the healthcare system to enhance access to our medicines, utilizing digital technologies to improve our drug discovery and development, as well as patient outcomes, and spearheading the conversation to advocate for pro-innovation/pro-patient policies. Every decision we make, and every step we take is done with the patient in mind—and to nurture an environment where breakthroughs can flourish.